Which of the Following Can Result in a Frameshift Mutation

When the RNA polymerase. Osteogenesis imperfecta from a frameshift mutation.

Genetic Mutation Worksheet Answer Key 12 5 Mutations Microbiology Canadian Edition Genetic Mutation Practices Worksheets Dna Project

The loss or gain of 1 or 2 nucleotides causes the affected codon and all of the codons that follow to be misread.

. However some insertional mutations can also be non-frameshift mutations. For example a substitution mutation is a type of non-frameshift mutation. Most genes are transcribed into segments of RNA ribonucleic acid which are.

Some DNA damage results in a modified nucleotide or small group of nucleotides that can not be read by RNA polymerase. In the illustration a stem-loop formed from an imperfect inverted repeat is mutated with a thymine T nucleotide insertion as a result of an inter- or intrastrand switch. Mutations in the collagen gene can lead to the disease Osteogenesis Imperfecta which is characterized by brittle bones.

Exposure to ionizing radiation such as gamma radiation can result in mutation possibly resulting in cancer or death. Rosenberg states These mechanisms reveal a picture of highly. This leads to a very different and often nonfunctional protein product.

Can be a mechanism for mutation if the transfer of material disrupts the coding sequence of the gene or if the transferred material itself contains one or more pathogenic variants. If the insertion is within a multiple of three. Whereas in former times mutations were assumed to occur by chance or induced by mutagens molecular mechanisms of mutation have been discovered in bacteria and across the tree of life.

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